PCPs provide better care through higher rates of medication intensification and lifestyle counseling. Covering physicians and midlevel providers may enable more frequent encounters when PCP resources are constrained (Diabetes Care)
Diabetes News
Category: Treatment
Effectiveness of gestational diabetes treatment: A systematic review
Treatment of GDM is effective in reducing macrosomia (high quality evidence), preeclampsia and shoulder dystocia. (Diabetes Research and Clinical Practice)
Closed-Loop Basal Insulin Delivery Over 36 Hours in Adolescents T1D
Day-and-night closed-loop basal insulin delivery can improve glucose control in adolescents. However, unannounced moderate-intensity exercise and excessive prandial boluses pose challenges to hypoglycemia-free closed-loop basal insulin delivery (Diabetes Care)
Long-Term Effects Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in T2D
Roux-en-Y gastric bypass and SG are associated with comparable remission rates of T2DM. However, insufficient weight loss or weight regain in those with a more advanced disease may hamper the benefits of these surgical techniques on T2DM (Annals of Surgery)
Diffuse near-infrared spectroscopy & of healing in diabetic foot ulcers
These data indicate that it could be possible to predict healing in 4 weeks using DNIRS, which can provide objective guidance toward the continuation of costly treatments (Wound Repair and Regeneration)
Endothelial Function in Newly Diagnosed T2D & Intensive Insulin Therapy
Intensive insulin therapy significantly improves endothelial injury/dysfunction as measured by vWF in early stage type 2 diabetes. Further study is needed to determine whether plasma vWF can help early identification, stratification and management of diabetic endothelial dysfunction (American Journal of Hypertension)
Reduction Carotid Intima-Media & Pancreatic Islet Transplantation
Islet transplantation may ameliorate diabetes-related atherosclerosis through improved glycemic control consequent to restoring endogenous insulin secretion, and optimal lipid management posttransplant also contributes (Diabetes Care)
Improved insulin sensitivity by the angiotensin receptor antagonist
Therapy with irbesartan improved insulin sensitivity in patients with chronic heart failure. Improved peripheral vasodilator capacity may contribute to the metabolic effect (International Journal of Cardiology)
Towards microRNA-based therapeutics for diabetic nephropathy
The discovery that modulation of miRNA expression in vivo is feasible, combined with recent results from successful clinical trials using this technology, opens the way for future novel therapeutic applications (Diabetologia)
Insulin pharmacodynamic profile & a novel infusion site warming device
Our results show that insulin infusion site warming with InsuPatch activation accelerates the time action profile of aspart insulin which may be of benefit to current open-loop and future closed-loop insulin delivery in patients with T1D (Pediatric Diabetes)
Strategies for Multivessel Revascularization in Diabetes
For patients with diabetes and advanced coronary artery disease, coronary-artery bypass grafting was superior to percutaneous coronary intervention in that it significantly reduced rates of death and myocardial infarction, with a higher rate of stroke (NEJM)
Dipeptidyl Peptidase 4 Inhibition may facilitate healing chronic foot ulcers
We have showed that DPP-4 inhibition accelerates healing of diabetic chronic ulcer, through induction of a histologic pattern consistent with enhanced angiogenesis. To the best of our knowledge, there has been no study evaluating the vildagliptin effect on the healing of foot ulcers in humans (Experimental Diabetes Research)
GIANT study efficacy of education of doctors about T2D management guidelines
A structured GP education programme did not improve HbA1c in patients with type 2 diabetes (Diabetes Research and Clinical Practice)
Pharmacists in primary care team reduces long-term risk of CV events T2D
Adding pharmacists to primary care teams for 1 year significantly reduced the predicted 10-year risk of cardiovascular events for patients with Type 2 diabetes without established cardiovascular disease (Diabetic Medicine)
Moderate-intensity physical activity ameliorates breast cancer risk
Moderate-intensity physical activity can substantially ameliorate the increased BC risk in diabetic women (Diabetes Care)
Management of Hyperglycemia, Dyslipidemia, and Albuminuria in Diabetes & CKD
Intensive glycemic control and lipid interventions did not improve clinical outcomes in patients with type 2 diabetes (American Journal of Kidney Diseases)
Communication
Facebook , Twitter, the last few years have shown the ease of communication using technology where all aspects of someone can be followed on line and where a person’s once confidential information now seems to be open to the world. Compare that to communication between health care professionals involved in a patients care.
Healing rate calculation in the diabetic foot ulcer: Comparing different methods
Contrary to expectations, the linear advancement method was correlated to initial wound size in the longer duration wounds suggesting that in these chronic wounds, differing healing phases render the surface area calculation method superior to the linear advancement parameter (Wound Repair and Regeneration)
Evaluating Regional Paediatric Diabetes Network Coordinator Yorkshire & Humber
A report on the findings of an evaluation of the impact of the Yorkshire and the Humber Paediatric Network Coordinator role (NHS Diabetes)
Effectiveness & Safety of Methods of Insulin Delivery and Glucose Monitoring
Continuous subcutaneous insulin infusion and MDI have similar effects on glycemic control and hypoglycemia, except CSII has a favorable effect on glycemic control in adults with type 1 diabetes mellitus. For glycemic control, rt-CGM is superior to SMBG and sensor-augmented insulin pumps are superior to MDI and SMBG without increasing the risk for hypoglycemia (Annals of Internal Medicine)