AADs were present in 58.13% of patients. Patients with LADA were more prone to a generalized autoimmune disorder than those with T1D. AADs development was significantly associated with female sex, older age and positive GADA, which proved an independent marker of associated autoimmunity (Diabetes Research and Clinical Practice)
Diabetes News
Tag: autoimmune
The Prevalence of Autoimmune Diseases in Longstanding Diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes
Lifetime risk of autoimmune disease in longstanding T1D approaches 50%, is greater in females, and is driven by thyroid disease. The probability of diabetes complications such as CVD was lower in those with autoimmune disease, which was driven mostly by non-thyroid autoimmune diseases (Canadian Journal of Diabetes)
DPP‐4 inhibitors lower the risk of autoimmune disease in patients with type 2 diabetes mellitus: A nationwide population‐based cohort study
In this large population‐based cohort study, upfront DPP4i combination therapy was associated with a lower risk of composite AD compared with initial non‐DPP4i combination therapy (British Journal of Clinical Pharmacology)
Higher cardiometabolic risk in idiopathic versus autoimmune type 1 diabetes: a retrospective analysis
Patients with IDM show many metabolic complications at onset, such as visceral obesity, hepatic steatosis and hypercholesterolemia and a higher cardiometabolic risk, than patients with ADM, similarly to patients with type 2 diabetes at onset (Diabetology & Metabolic Syndrome)
Autoimmune Diseases in Children and Adults with Type 1 Diabetes from the T1D Exchange Clinic Registry
Results of this study have implications for both primary care and endocrine practice and will allow clinicians to better anticipate and manage the additional autoimmune diseases that develop in patients with T1D (Journal of Clinical Endocrinology & Metabolism)
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