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Diabetes News

Tag: Type 1 Diabetes


Care of diabetes in children and adolescents: controversies, changes, and consensus

May 23rd 2015

The management of diabetes remains a substantial burden on children with diabetes and their families, despite improvements in treatment and rates of morbidity and mortality (The Lancet)

Categories: News, Paediatrics
Tags: Type 1 Diabetes, Type 2 Diabetes

Categories: Paediatrics
Tags: Type 1 Diabetes, Type 2 Diabetes

Type 1 Diabetes at a Crossroads!

May 23rd 2015

What then are the major advances in type 1 diabetes? How close are we to realizing an intervention that can delay or prevent type 1 diabetes? Are we any closer to a cure today than we were 10 years ago?  (Diabetes Care)

Categories: News, Reports
Tags: Type 1 Diabetes

Categories: Reports
Tags: Type 1 Diabetes

Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes

May 19th 2015

Mean GA levels were more closely associated with DN progression than mean HbA1c in subjects with T1D. However, they were not associated with the CAA (Cardiovascular Diabetology)

Categories: Monitoring, News
Tags: Glycated albumin, HbA1c, Type 1 Diabetes

Categories: Monitoring
Tags: Glycated albumin, HbA1c, Type 1 Diabetes

Twice- rather than once-daily basal insulin is associated with better glycaemic control in Type 1 diabetes mellitus 12 months after skills-based structured education in insulin self-management

May 18th 2015

After structured education in adults with Type 1 diabetes mellitus, use of basal insulin twice rather than once daily was associated with lower HbA1c, independent of insulin type, with significant reductions in severe hypoglycaemia and ketoacidosis in all groups (Diabetic Medicine)

Categories: News, Treatment
Tags: insulin, Type 1 Diabetes

Categories: Treatment
Tags: insulin, Type 1 Diabetes

Role of the gastrointestinal ecosystem in the development of type 1 diabetes

May 11th 2015

This review examines the current knowledge of the role of the GI ecosystem in T1D and indicates the extensive opportunities for further investigation that could lead to biomarkers and therapeutic interventions for disease prevention and/or modulation (Pediatric Diabetes)

Categories: News, Research
Tags: biomarkers, GI ecosystem, Type 1 Diabetes

Categories: Research
Tags: biomarkers, GI ecosystem, Type 1 Diabetes

Intensive Diabetes Therapy and Ocular Surgery in Type 1 Diabetes

April 30th 2015

Intensive therapy in patients with type 1 diabetes was associated with a substantial reduction in the long-term risk of ocular surgery (New England Journal of Medicine)

Categories: News, Treatment
Tags: Intensive therapy, Type 1 Diabetes

Categories: Treatment
Tags: Intensive therapy, Type 1 Diabetes

The relationship between the frequency of self-monitoring of blood glucose and glycemic control in patients with type 1 diabetes mellitus on continuous subcutaneous insulin infusion or on multiple daily injections

April 14th 2015

An SMBG frequency of <3.5 times per day appeared to be a risk factor for poor glycemic control (HbA1c ≥8%) in type 1 diabetes mellitus patients on CSII (Journal of Diabetes Investigation)

Categories: Monitoring, News
Tags: SMBG, Type 1 Diabetes

Categories: Monitoring
Tags: SMBG, Type 1 Diabetes

Social Media and Diabetes

March 29th 2015

Can Facebook and Skype Improve Glucose Control in Patients With Type 1 Diabetes on Pump Therapy? One-Year Experience (Diabetes Care)

Categories: Management, News
Tags: pumps, social media, Type 1 Diabetes

Categories: Management
Tags: pumps, social media, Type 1 Diabetes

Reduction of hypoglycaemic events with a behavioural intervention: a randomized clinical trial for paediatric patients with Type 1 diabetes mellitus

March 13th 2015

Our findings suggest the need for a long-term (> 1 year) focus on the implementation of interventions targeting diabetes management in young people. Behavioural interventions targeting problem-solving skills could be considered as practical, non-pharmacological strategies to reduce hypoglycaemia in adolescents with Type 1 diabetes (Diabetic Medicine)

Categories: Management, News
Tags: hypoglycemia, interventions, Type 1 Diabetes

Categories: Management
Tags: hypoglycemia, interventions, Type 1 Diabetes

Glomerular haemodynamic profile of patients with Type 1 diabetes compared with healthy control subjects

February 10th 2015

Hyperfiltration in Type 1 diabetes is primarily driven by alterations in afferent arteriolar resistance rather than efferent arteriolar resistance. Renal protective therapies should focus on afferent renal arteriolar mechanisms through the use of pharmacological agents that target tubuloglomerular feedback, including sodium-glucose cotransporter 2 inhibitors and incretins (Diabetic Medicine)

Categories: Nephropathy, News
Tags: renal, Type 1 Diabetes

Categories: Nephropathy
Tags: renal, Type 1 Diabetes

Diabetes reversal via gene transfer: building on successes in animal models

February 1st 2015

The aim of this review is to evaluate the success of cell and gene therapy to reverse T1D in animal models for future clinical application (Dove Press)

Categories: Genetics, News
Tags: Type 1 Diabetes

Categories: Genetics
Tags: Type 1 Diabetes

Bariatric surgery and diabetes: Implications of type 1 versus insulin-requiring type 2

January 23rd 2015

Our study suggests that improved glycemic control may not be an expected outcome when considering bariatric surgery in patients with DM1; however, additional investigation is warranted (Obesity)

Categories: Bariatric, News
Tags: obesity, Type 1 Diabetes

Categories: Bariatric
Tags: obesity, Type 1 Diabetes

Effect of Subcutaneous Insulin Detemir on Glucose Flux and Lipolysis during Hyperglycaemia in People with Type 1 Diabetes

January 20th 2015

The results are also consistent with the hypothesis that detemir has a lesser effect on the periphery, as evidenced by a lesser effect on peripheral glucose uptake at specific glucose concentrations (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: Insulin Detemir, Type 1 Diabetes

Categories: Medication
Tags: Insulin Detemir, Type 1 Diabetes

Insulin secretion in patients with latent autoimmune diabetes (LADA): half way between type 1 and type 2 diabetes: action LADA 9

January 14th 2015

The present study shows that the magnitude of stimulated insulin secretion in LADA is intermediate between that of type 1 and type 2 diabetes mellitus (BMC Endocrine Disorders)

Categories: News, Pathology
Tags: lada, Type 1 Diabetes, Type 2 Diabetes

Categories: Pathology
Tags: lada, Type 1 Diabetes, Type 2 Diabetes

Circulating dipeptidyl peptidase-4 activity is associated with insulin resistance in type 1 diabetic patients

January 13th 2015

Serum DPP4 activity is associated with IR in T1DM patients and it might play an important role in its pathophysiology (Diabetes and Its Complications)

Categories: News, Pathology
Tags: DPP4, Insulin resistance, Type 1 Diabetes

Categories: Pathology
Tags: DPP4, Insulin resistance, Type 1 Diabetes

Cardiac Autonomic Dysfunction Is Associated With High-Risk Albumin-to-Creatinine Ratio in Young Adolescents With Type 1 Diabetes in AdDIT (Adolescent Type 1 Diabetes Cardio-Renal Interventional Trial)

January 13th 2015

Adolescents at potentially higher risk for nephropathy show an adverse cardiac autonomic profile, indicating sympathetic overdrive, compared with the lower-risk group. Longitudinal follow-up of this cohort will further characterize the relationship between autonomic and renal dysfunction and the effect of interventions in this population (Diabetes Care)

Categories: Cardiovascular, Nephrology, News
Tags: albumin, Cardiovascular, creatinine, Type 1 Diabetes

Categories: Cardiovascular, Nephrology
Tags: albumin, Cardiovascular, creatinine, Type 1 Diabetes

Plasma Levels of MASP-1 and MASP-2 are Elevated in Type 1 Diabetes and Correlate with Glycaemic Control

January 13th 2015

MASP-1 and MASP-2 levels were significantly higher in children and adults with T1DM than in their respective control groups (Clinical and Experimental Immunology)

Categories: Biochemistry, News
Tags: glycaemic control, Type 1 Diabetes

Categories: Biochemistry
Tags: glycaemic control, Type 1 Diabetes

Corneal Confocal Microscopy Predicts 4-Year Incident Peripheral Neuropathy in Type 1 Diabetes

January 13th 2015

DPN can be predicted by various demographic, metabolic, and conventional neuropathy measures. The ability of CCM to predict DPN broadens the already impressive diagnostic capabilities of this novel ophthalmic marker (Diabetes Care)

Categories: Neuropathy, News, Ophthalmology
Tags: Type 1 Diabetes

Categories: Neuropathy, Ophthalmology
Tags: Type 1 Diabetes

NICE guideline consultations

January 11th 2015

Type 1 Diabetes – Type 2 Diabetes – Diabetes in children and young people – Diabetic foot problems

Categories: Guidelines, News, Paediatrics
Tags: Type 1 Diabetes, Type 2 Diabetes

Categories: Guidelines, Paediatrics
Tags: Type 1 Diabetes, Type 2 Diabetes

Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison

January 7th 2015

These results suggest that there are substantial variations in glycaemic control among people with Type 1 diabetes between the data sources and that there is room for improvement in all populations, especially in young adults (Diabetic Medicine)

Categories: Audits, News
Tags: glycaemic control, Type 1 Diabetes

Categories: Audits
Tags: glycaemic control, Type 1 Diabetes
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