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Diabetes News

Tag: Type 2 Diabetes


Genomic risk score provides predictive performance for type 2 diabetes in the UK biobank

January 4th 2021

The metaGRS significantly improves T2D prediction ability (Acta Diabetologica)

Categories: Genetics, News
Tags: Type 2 Diabetes

Categories: Genetics
Tags: Type 2 Diabetes

Comparing the bone mineral density among male patients with latent autoimmune diabetes and classical type 1 and type 2 diabetes, and exploring risk factors for osteoporosis

January 3rd 2021

Compared with male patients with T2DM, lower BMDs were observed in patients with LADA and T1DM. Low BMI, uric acid, C-peptide levels, and high osteocalcin levels are risk factors for developing low BMD in male patients with diabetes (Journal of Endocrinological Investigation)

Categories: News, Pathology
Tags: lada, Osteoporosis, Type 1 Diabetes, Type 2 Diabetes

Categories: Pathology
Tags: lada, Osteoporosis, Type 1 Diabetes, Type 2 Diabetes

Diabetes (type 1 and type 2) in children and young people: diagnosis and management

December 16th 2020

This guideline covers the diagnosis and management of type 1 and type 2 diabetes in children and young people aged under 18 (NICE)

Categories: News, Paediatrics
Tags: Type 1 Diabetes, Type 2 Diabetes

Categories: Paediatrics
Tags: Type 1 Diabetes, Type 2 Diabetes

Prediction of Heart Failure Outcomes in Patients with Type 2 Diabetes Mellitus: Validation of the TRS‐HFDM Score in the ACCORD Trial

December 13th 2020

The TRS‐HFDM discriminates for HF specific risk among people with T2DM. Using the TRS‐HFDM to identify those who maximally benefit from therapies that reduce HF risk warrants evaluation (Diabetes, Obesity and Metabolism)

Categories: Cardiovascular, News
Tags: ACCORD, Type 2 Diabetes

Categories: Cardiovascular
Tags: ACCORD, Type 2 Diabetes

Comparative Efficacy of Dual and Single Initiation of Add-On Oral Antihyperglycemic Agents in Type 2 Diabetes Uncontrolled on Metformin Alone: A Systematic Literature Review and Network Meta-Analysis

December 13th 2020

For reduction of HbA1c, weight, and SBP in patients uncontrolled on metformin, add-on dual AHAs showed greater improvement compared to single AHAs. These findings can further inform the treatment of T2DM patients uncontrolled on metformin (Diabetes Therapy)

Categories: Medication, News
Tags: Type 2 Diabetes

Categories: Medication
Tags: Type 2 Diabetes

Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses

December 10th 2020

In this study, we observed that in patients with obesity and T2DM-Ins, bariatric surgery was associated with high rates of postoperative cessation of insulin therapy, which is, in turn, a major driver of overall reductions in direct healthcare cost. Our findings suggest that a strategy utilising bariatric surgery for patients with obesity and T2DM-Ins is cost saving to the national healthcare provider (National Health Service (NHS)) over a 5-year time horizon (PLOS Medicine)

Categories: Bariatric, News
Tags: Type 2 Diabetes

Categories: Bariatric
Tags: Type 2 Diabetes

Impact of Ramadan‐focused diabetes education on hypoglycemia risk and metabolic control for patients with type 2 diabetes mellitus: A systematic review

December 8th 2020

Ramadan‐focused diabetes education had a significant impact on hypoglycemia and glycaemic control, with no significant effect on body weight, blood lipids or blood pressure (International Journal of Clinical Practice)

Categories: Education, News
Tags: hypoglycemia, Ramadan, Type 2 Diabetes

Categories: Education
Tags: hypoglycemia, Ramadan, Type 2 Diabetes

Potential biomarker in serum for predicting susceptibility to type 2 diabetes mellitus: Free fatty acid 22:6

December 8th 2020

C22:6 can be an independent risk factor for type 2 diabetes mellitus, and it has a great potential to predict the susceptibility to type 2 diabetes mellitus (Journal of Diabetes Investigation)

Categories: News, Screening
Tags: Type 2 Diabetes

Categories: Screening
Tags: Type 2 Diabetes

Cost-Effectiveness of Canagliflozin Added to Standard of Care for Treating Diabetic Kidney Disease (DKD) in Patients with Type 2 Diabetes Mellitus (T2DM) in England: Estimates Using the CREDEM-DKD Model

December 3rd 2020

Model results suggest that adding canagliflozin 100 mg to SoC can improve patient outcomes while reducing overall net costs from the NHS perspective in England (Diabetes Therapy)

Categories: News, Treatment
Tags: canagliflozin, DKD, Type 2 Diabetes

Categories: Treatment
Tags: canagliflozin, DKD, Type 2 Diabetes

Efficacy and Safety of the Newer Oral Hypoglycemic Agents in Patients with T2DM During Ramadan: A Systematic Review and Meta-analysis

November 30th 2020

This systematic review and meta-analysis shows clinical benefits with the glucose lowering medications in patients with T2DM who fast during Ramadan (Diabetes Research and Clinical Practice)

Categories: Medication, News
Tags: Ramadan, Type 2 Diabetes

Categories: Medication
Tags: Ramadan, Type 2 Diabetes

Risk Factor Control and Cardiovascular Event Risk in People With Type 2 Diabetes in Primary and Secondary Prevention Settings

November 24th 2020

Risk Factor Control and Cardiovascular Event Risk in People With Type 2 Diabetes in Primary and Secondary Prevention Settings (Circulation)

Categories: Cardiovascular, News
Tags: Type 2 Diabetes

Categories: Cardiovascular
Tags: Type 2 Diabetes

Type 1 and type 2 diabetes after gestational diabetes: a 23 year cohort study

November 20th 2020

All women with GDM should be intensively monitored for a decade, after which the risk for type 1 diabetes is minimal. However, the incidence of type 2 diabetes remains linear, and therefore individualised lifelong follow-up is recommended (Diabetologia)

Categories: Gestational, Monitoring, News
Tags: Type 1 Diabetes, Type 2 Diabetes

Categories: Gestational, Monitoring
Tags: Type 1 Diabetes, Type 2 Diabetes

Effects of empagliflozin on first and recurrent clinical events in patients with type 2 diabetes and atherosclerotic cardiovascular disease: a secondary analysis of the EMPA-REG OUTCOME trial

November 18th 2020

Empagliflozin reduced the total burden of cardiovascular complications and all-cause admission to hospital in patients with type 2 diabetes and atherosclerotic cardiovascular disease (The Lancet Diabetes & Endocrinology)

Categories: Medication, News
Tags: Empagliflozin, Type 2 Diabetes

Categories: Medication
Tags: Empagliflozin, Type 2 Diabetes

Serum Uric Acid concentration is associated with insulin resistance and impaired insulin secretion in adults at risk for Type 2 Diabetes

November 18th 2020

Serum uric acid concentration is significantly associated with IR and impaired insulin secretion, but not with beta-cell dysfunction, in subjects at risk for developing T2DM (Primary Care Diabetes)

Categories: Monitoring, News
Tags: Type 2 Diabetes, uric acid

Categories: Monitoring
Tags: Type 2 Diabetes, uric acid

Lipid Profile in Indian Patients With Type 2 Diabetes: The Scope for Atherosclerotic Cardiovascular Disease Risk Reduction

November 18th 2020

In South Indian patients with type 2 diabetes and fair glycemic control, high LDL cholesterol is the predominant lipid abnormality. There remains a huge potential for ASCVD risk reduction in this population if the knowledge practice gap is addressed (Diabetes Spectrum)

Categories: Cardiovascular, News
Tags: lipid, Type 2 Diabetes

Categories: Cardiovascular
Tags: lipid, Type 2 Diabetes

Lifestyle Intervention With or Without Lay Volunteers to Prevent Type 2 Diabetes in People With Impaired Fasting Glucose and/or Nondiabetic Hyperglycemia

November 12th 2020

The Norfolk Diabetes Prevention lifestyle intervention reduced the risk of type 2 diabetes in current high-risk glycemic categories. Enhancing the intervention with DPM did not further reduce diabetes risk. These translatable results are relevant for current diabetes prevention efforts (JAMA)

Categories: Management, News
Tags: Type 2 Diabetes

Categories: Management
Tags: Type 2 Diabetes

Risk of cardiac autonomic neuropathy in latent autoimmune diabetes in adults is similar to type 1 diabetes and lower compared to type 2 diabetes: a cross sectional study

November 11th 2020

This is the first study offering a comparative evaluation of cardiac autonomic neuropathy among LADA, type 1 and type 2 diabetes, showing a lower risk of cardiac autonomic neuropathy in LADA compared to type 2 diabetes and similar compared to type 1 diabetes. This disparity was not due to differences in age, metabolic control or cardiovascular risk factors (Diabetic Medicine)

Categories: Cardiovascular, News
Tags: lada, Type 1 Diabetes, Type 2 Diabetes

Categories: Cardiovascular
Tags: lada, Type 1 Diabetes, Type 2 Diabetes

Durability of glycaemic control in type 2 diabetes: A systematic review and meta‐analysis for its association with body weight changes

November 11th 2020

Modest weight loss with a goal of 2‐3% of body weight should be recommended to improve therapeutic durability and prevent beta‐cell deterioration (Diabetes, Obesity and Metabolism)

Categories: News, Obesity
Tags: glycaemic control, Type 2 Diabetes

Categories: Obesity
Tags: glycaemic control, Type 2 Diabetes

Sodium-glucose cotransporter 2 inhibitor versus metformin as first-line therapy in patients with type 2 diabetes mellitus: a multi-institution database study

November 10th 2020

In patients with T2DM, SGLT2i as first-line treatment may be associated with decreased events of heart failure hospitalization, acute coronary syndrome, and all-cause mortality, compared with metformin as first-line treatment. However, there may be an increased events of ischemic stroke using SGLT2i compared to metformin (Cardiovascular Diabetology)

Categories: Medication, News
Tags: SGLT2 inhibitors, Type 2 Diabetes

Categories: Medication
Tags: SGLT2 inhibitors, Type 2 Diabetes

Integrated personalized diabetes management goes Europe: A multi-disciplinary approach to innovating type 2 diabetes care in Europe

November 10th 2020

Building on an iterative six-step disease management process that leverages feedback loops and utilizes commodity digital tools, the PDM-ProValue study program demonstrated that integrated personalized diabetes management, or iPDM, can improve the standard of care for persons living with diabetes in a sustainable way (Primary Care Diabetes)

Categories: News, Treatment
Tags: Type 2 Diabetes

Categories: Treatment
Tags: Type 2 Diabetes
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